Treatment Scores are about coming up with a statistic that patients can understand, since the math of medical statistics can be ridiculous. Here is my first attempt to explain a (November 29, 2022) pragmatic #COVID mask study. It's about N95 masks versus medical masks. There were about 500 patients in each group.
The primary outcome was confirmed COVID-19 on reverse transcriptase polymerase chain reaction (RT-PCR) test.
The primary outcome in the intention-to-treat analysis, RT-PCR–confirmed COVID-19, occurred in 52 of 497 (10.46%) in the medial mask group versus 47 of 507 (9.27%) in the N95 respirator group (HR, 1.14 [95% CI, 0.77 to 1.69]).
So, N95 masks were 1.19% better than medical masks in this study for the outcome measured.
https://www.acpjournals.org/doi/10.7326/M22-1966
The primary outcome is a test. It is not whether the patient lives or dies. So, one always has to ask, does the primary outcome make a difference to the patient in the real world?
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