Your gut bacteria may be causing the discs of your spine to degenerate.
I'm BradMD, retired physician and economist, and I love medical journal club.
Why do so many people have back pain or neck pain? The article that I link to below suggests that the bacteria in your gut can cause disease of your spine by somehow causing the discs between your vertebrae to degenerate.
The study, which has very interesting statistical methods, which on the surface suggest that it is better than many other such studies, found that the phylum Bacteroidetes was associated with generative disc disease.
You may remember that the animal kingdom goes: phylum > class > order > family > genus > species.
The phylum Bacteroidetes contains Bacteroides fragilis, Prevotella species, and Flavobacterium species.
This is fascinating, because I suspect that probiotics, which are a kind of bacterial supplement many people are taking today, are becoming very important to human health, and I believe that the Human Microbiome Project, and other such research, is going to help us become healthier than we are today.
To be perfectly accurate, let me add the human microbiome, while mostly in your digestive tract, also includes all the microbes everywhere else inside or outside your body.
-BradMD
REFERENCE:
Gut microbiota and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/37580794/ 
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